Nevertheless, the principle behind resonance stabilization is the same in both cases.
2.
Especially when there is more than one major contributor, the resonance stabilization is high.
3.
Reduction in resonance stabilization of pyrimidines may lead to addition and ring cleavage reactions rather than substitutions.
4.
Similar tautomeric rearrangement and pi-resonance stabilization would then give the ion some degree of stability.
5.
These rings are very stable due to resonance stabilization, so they are difficult to break down.
6.
One explanation for the increased acidity over alcohols is resonance stabilization of the phenoxide anion by the aromatic ring.
7.
Resonance stabilization, however, enables weaker bases such as carboxylates; for example, sodium acetate is a weak base.
8.
This effect is due to a number of factors including increased resonance stabilization and solvation of the products relative to the reactants.
9.
Due to its resonance stabilization, the peptide bond is relatively unreactive under physiological conditions, even less than similar compounds such as esters.
10.
Esters exhibit less resonance stabilization than amides, so the formation of a tetrahedral intermediate and subsequent loss of resonance is not as energetically unfavorable.
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